Intoxication by Intraperitoneal Injection or Oral Gavage Equally Potentiates Postburn Organ Damage and Inflammation
نویسندگان
چکیده
منابع مشابه
Intoxication by Intraperitoneal Injection or Oral Gavage Equally Potentiates Postburn Organ Damage and Inflammation
The increasing prevalence of binge drinking and its association with trauma necessitate accurate animal models to examine the impact of intoxication on the response and outcome to injuries such as burn. While much research has focused on the effect of alcohol dose and duration on the subsequent inflammatory parameters following burn, little evidence exists on the effect of the route of alcohol ...
متن کاملModulation of Inflammation by Alcohol Exposure
The morbidity and mortality resulting from alcohol-related diseases globally impose a substantive cost to society [1, 2]. Alcohol consumption is a major risk factor for all types of injuries [3] and excessive alcohol consumption is the third leading cause of preventable death worldwide. Besides its multiorgan system effects, ethanol exposure is known to cause changes in the physiological respon...
متن کاملInflammation, immunity, and hypertensive end-organ damage.
For >50 years, it has been recognized that immunity contributes to hypertension. Recent data have defined an important role of T cells and various T cell-derived cytokines in several models of experimental hypertension. These studies have shown that stimuli like angiotensin II, deoxycorticosterone acetate-salt, and excessive catecholamines lead to formation of effector like T cells that infiltr...
متن کاملMacrophages and fibroblasts during inflammation, tissue damage and organ injury.
Inflammation is a highly complex cellular surveillance system that is essential for anti-microbial defense and wound healing. The inflammatory process relies on multifaceted coordination among various body systems. Many host cells including leukocytes, fibroblasts, endothelial cells and epithelial cells are involved in the inflammatory process. Cellular receptors, such as Toll-Like-Receptors (T...
متن کاملQuercetin Potentiates Hepatoprotective and Antioxidant Response to Intraperitoneal, Intravenous, Subcutaneous and Oral Administration in Wistar Rats
This study investigated the hepatoprotective and antioxidant response to intraperitoneal, intravenous, subcutaneous and oral treatment with quercetin in adult male Wistar rat. The animals were divided randomly into the four groups according to the routes of administration. Quercetin was allowed to react with selected hepatic isoenzymes (aspartate amino transferase, alanine amino transferase) vi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 2013
ISSN: 0962-9351,1466-1861
DOI: 10.1155/2013/971481